Quality of Life
Description
EORTC research around Quality of Life aims to:
- Develop and refine questionnaires to assess patients’ health-related quality of life in oncology clinical trials, other well-designed research studies and clinical practice
- Collaborate with other EORTC research groups in implementing health-related quality of life studies within their clinical trial programs
- Conduct research to better understand the effects of cancer and its treatment on the health-related quality of life of diverse populations of patients with cancer, across different cultures.
Professionals from various disciplines, including oncologists, radiotherapists, surgeons, psychiatrists, palliative care specialists, psychologists, social workers and research methodologists are involved in developing disease-specific treatment measurement modules to be administered in addition to the core quality of life questionnaire, the EORTC QLQ-C30. The modules, like the core questionnaire, are designed for use in cancer clinical trials, clinical practice and academic research.
Recruiting Clinical Trials
All clinical trials in this research field-
Cohort
Follow-up in Gynecological Cancer Survivors: An EORTC QLG-GCG Survivorship Study
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Cohort
Follow-up in Early and Locally Advanced Breast Cancer Patients: An EORTC QLG-BCG- ROG Protocol
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Cohort
A Survivorship Project to understAnd and to impRove long-Term outcomes for Acute myeloid leukemia patients (SPARTA): The SPARTA Platform
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Cohort
Late Toxicity and Long-term Quality of Life in Head and Neck Cancer Survivors
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Cohort
Comparative evaluation of the computer-adaptive EORTC quality of life measures
Main Achievements
EORTC research in Quality of Life has led to the creation of the EORTC Quality of Life Questionnaire ( link to TOOLS – EORTC QLQ-C30), which has become one of the standard tools to measure quality of life in cancer clinical trials. The core questionnaire, currently available in over 100 languages, is accompanied by more than 20 fully-validated modules (link to appropriate section on QOL website), addressing disease or population-specific concerns.
Related Projects
SISAQOL : Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life endpoints Data for Cancer Clinical Trials
Research Group
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ChairLonneke Van De Poll-Franse
Comprehensive Cancer Centre South
Eindhoven, Netherlands
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SecretaryKrzysztof Tomaszewski
Jagiellonian University Medical College
Cracow, Poland
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TreasurerBernhard Holzner
Innsbruck Medical University
Innsbruck, Austria
Test
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A. Brandes - Bologna, IT
Ospedale Bellaria
Test2
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A. Bottomley - Brussels, BE
Notable Publications
All publications on this research field-
2021
Demystifying the estimand framework: a case study using patient-reported outcomes in oncology
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2020
Minimally important differences for interpreting European Organisation for Research and Treatment of Cancer (EORTC) Quality of life Questionnaire core 30 scores in patients with ovarian cancer
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2020
Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling
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2020
Objective neurocognitive functioning and neurocognitive complaints in patients with high-grade glioma: Evidence of cognitive awareness from the European Organisation for Research and Treatment of Cancer brain tumour clinical trials
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2020
An international update of the EORTC questionnaire for assessing quality of life in breast cancer patients: EORTC QLQ-BR45