Cross-discipline

Infectious diseases

Description

Infections can be a significant problem for patients undergoing treatment for cancer. Research conducted by EORTC in Infectious Diseases aims to improve our understanding and management of such infectious complications.

Main Achievements

EORTC studies in infectious diseases dramatically changed the outcome for patients by significantly decreasing mortality due to septicemia.

They include:

  • A landmark study comparing three antibiotic treatments for fever during neutropenia and presumed infection. The trial found an association with shock, temperature measure, and granulocyte and platelet counts at the onset of fever and gram-negative bacteremia. (link to publication)
  • A large international trial which established voriconazole as the standard of treatment for proven and probable aspergillosis. (link to publication)

An EORTC study established definitions of invasive fungal disease in cancer patients, which has helped advance epidemiological, diagnostic and clinical research.

Our research has also helped improve the management of infections in cancer patients by better identifying risks and evaluating different treatment strategies.

Research Group

Group documents
  • Chair

    Peter Donnelly

    Radboud University Nijmegen Medical Centre

    Nijmegen, Netherlands

  • Secretary

    Matteo Bassetti

    Azienda Ospedaliera Universitaria San Martino

    Genova, Italy

  • Treasurer

    Oscar Marchetti

    Centre Hospitalier Universitaire Vaudois

    Lausanne, Switzerland