EORTC studies opened since 12 March 2010
Randomized Phase III trial comparing immediate versus deferred nephrectomy in patients with synchronous metastatic renal cell carcinoma.
Target Accrual: 458 patients
Study Coordinators:
- Axel Bex – The Netherlands Cancer Institute – Antoni Van Leeuwenhoekziekenhuis, Amsterdam
- John B.A.G. Haanen – The Netherlands Cancer Institute – Antoni Van Leeuwenhoekziekenhuis, Amsterdam
Studies in regulatory process
Phase III Intergroup Study of Radiotherapy versus Temozolomide Alone versus Radiotherapy with Concomitant and Adjuvant Temozolomide for Patients with Newly Diagnosed Anaplastic Oligodendroglioma or Anaplastic Mixed Glioma with Chromosomal Co-delections of 1p and 19q.
Target Accrual: 544 patients
Study Coordinator:
- Martin J. Van den Bent – Erasmus University Medical Center, Rotterdam
- Frederic Dhermain – Institut Gustave Roussy, Villejuif
- Wolfgang Wick – Universitaetsklinikum Heidelberg – Kopfklinik, Heidelberg
Clinical and biological characterization of Male Breast Cancer: an international retrospective EORTC, BIG and NABCG intergroup study.
Target Accrual: 1800 patients
Study Coordinator:
- Fatima Cardoso – Institut Jules Bordet – Brussels
A phase III study of Ienalidomide maintenance after debulking with gemcitabine or liposomal doxorubicin +/- radiotherapy in patients with advanced cutaneous T-cell lymphoma not previously treated with intravenous chemotherapy
Target Accrual: 100 patients
Study Coordinator:
- Martine Bagot – Hôpital Saint-Louis (AP-HP), Paris
Effectiveness of first line treatment with lapatinib and ECF/X in metastatic gastric cancer according to HER2 and EGFR status: a randomized phase II trial
Target Accrual: 228 patients
Study Coordinator:
- Arnaud Roth – Hôpital Cantonal Universitaire De Genève, Genève
Randomized Phase III trial on postoperative chemoradiation in combination with anti EGFR-antibody versus postoperative chemoradiation in head and neck squamous cell carcinomas (HNSCC) with high risk of locoregional recurrence
Target Accrual: 800 patients for the main study, 150 patients for the pre-study
Study Coordinators:
- Wilfried Budach – Heinrich-Heine Universitaetsklinik Dusseldorf, Duesseldorf
- Johannes Langendijk – University Medical Center Groningen, Groningen
- Carla Van Herpen – Radboud University Nijmegen Medical Center, Nijmegen